Research & Validation

Clinical Studies

A comprehensive library of peer-reviewed clinical studies, meta-analyses, and medical abstracts validating the efficacy of Sustained Acoustic Medicine.

Level 1A

Meta-Analysis

Sustained acoustic medicine for the treatment of musculoskeletal injuries: a systematic review and meta-analysis

View Publication →

Low-Intensity Continuous Ultrasound Therapies-A Systemic Review of Current State-of-the-Art and Future Perspectives

View Publication →

Sustained acoustic medicine as a nonsurgical and non-opioid knee osteoarthritis treatment option: a health economic cost effectiveness analysis for symptom management

View Publication →

The Effects of Low-Intensity Therapeutic Ultrasound on Measurable Outcomes: A Critically Appraised Topic

View Publication →

Low Intensity Ultrasound for Promoting Soft Tissue Healing: A Systematic Review of the Literature and Medical Technology

View Publication →

Level 1B

RCTs

Sustained acoustic medicine treatment of discogenic chronic low back pain: A randomized, multisite, double-blind, placebo-controlled trial

View Publication →

Long Duration Sonophoresis of Diclofenac to Augment Rehabilitation of Common Musculoskeletal Injuries

View Publication →

Long Duration Ultrasound Combined with Platelet-Rich Plasma Injection for Return to Sport after Soft Tissue Injury

View Publication →

Clinical Diathermy Performance Evaluation of Multi-hour Sustained Acoustic Medicine Treatment with 2.5% Diclofenac Ultrasound Coupling Patch

View Publication →

Low-Intensity Continuous Ultrasound for the Symptomatic Treatment of Upper Shoulder and Neck Pain: A Randomized, Double-Blind Placebo-Controlled Clinical Trial

View Publication →

Effect of low-intensity long-duration ultrasound on the symptomatic relief of knee osteoarthritis: a randomized, placebo-controlled double-blind study

View Publication →

Level 4

Clinical Studies

Evaluation of Sustained Acoustic Medicine for Treating Musculoskeletal Injuries in Military and Sports Medicine

View Publication →

Critical survey and panel review of sustained acoustic medicine in the treatment of sports-related musculoskeletal injuries by professional sports athletic trainers

View Publication →

Sustained Acoustic Medicine Combined with A Diclofenac Ultrasound Coupling Patch for the Rapid Symptomatic Relief of Knee Osteoarthritis: Multi-Site Clinical Efficacy Study

View Publication →

Efficacy of Sustained Acoustic Medicine as an Add-on to Traditional Therapy in Treating Sport-related Injuries

View Publication →

Level 5

Pilot Studies

Skin temperature increase mediated by wearable, long duration, low-intensity therapeutic ultrasound

View Publication →

Sustained acoustic medicine: wearable, long duration ultrasonic therapy for the treatment of tendinopathy

View Publication →

Pilot Clinical Studies of Long Duration, Low Intensity Therapeutic Ultrasound for Osteoarthritis

View Publication →
Comparison

The Clear Choice for Healing

Feature sam® Treatment Traditional Therapy Surgical Intervention
Duration 1-4 hours daily wearable therapy 30-60 minutes per session Hours + extended recovery time
Infrastructure Portable wearable device Clinic dependent Hospital required
Recovery Time Faster return to daily activities Moderate recovery timeline Extended downtime required
Portability Highly portable, usable anywhere Not portable Not portable
Long-Term Use Supports chronic condition management Limited long-term benefit Not applicable
Downtime Minimal to none Requires time per session Significant downtime
Live Yes with Arthritis Podcast
Featured Spotlight

Proud Sponsor of the "Live Yes with Arthritis" Podcast

In this episode sponsored by ZetrOZ Systems, we get answers about what exactly arthritis is, what it isn't, and what people misunderstand about this group of chronic diseases. Join the conversation with the Arthritis Foundation to learn more about non-invasive recovery.